"G. d'Annunzio"
Basic knowledge of genetics.
Students should know the laws of inheritance, the structure and functions of DNA and chromosomes, mutations and genetic diseases, the main chromosomal syndromes, the main techniques of molecular biology and cytogenetics and their practical applications.
The laws of inheritance, structure and functions of DNA and chromosomes, mutations and genetic diseases, major chromosomal syndromes.
-Nucleic acids. DNA and RNA, structure, synthesis and duplication. Chromatin, heterochromatin, euchromatin. - Gene structure. Protein synthesis, genetic code, regulation of gene expression. -Cytogenetics. Cytogenetic techniques and their applications, normal human karyotype. - Chromosomal abnormalities. Numerical and structural alterations of chromosomes. Main chromosomal syndromes. Chromosomal alterations and spontaneous abortions. - Invasive and non-invasive prenatal diagnosis. - Mendel laws. Autosomal dominant and recessive inheritance, heterosomal inheritance, mitochondrial inheritance. Polygenic inheritance. Particularity of the Mendel laws. -Mutations. Point mutations, frameshift, dynamics. Chemical and physical mutagens. - Molecular biology techniques and their applications. Gene cloning. - Oncogens and oncosuppressors.
Clementi. Elementi di Genetica Medica. Edises. Slides will be provided to the students.
Frontal lessons
Oral examination
No
