Pharmacokinetics: Routes of drug administration.
Absorption - Distribution - Biotransformation - Elimination of drugs, with particular reference to possible interactions with foods.
Main pharmacokinetic parameters.
Pharmacodynamics: General principles of the action of drugs, molecular targets of drugs: concept of receptor. Drug-receptor interactions. Dose-response curve. Agonist drugs and antagonist drugs.
Principles of Pharmacogenomics
Pharmacological research: from the idea to the product
- Drug discovery;
- The development of a drug: the preclinical phase and clinical development (phases, structures and agents, methodology).
- National and multi-state registration;
- Marketing
- Pharmacovigilance
Non-steroidal anti-inflammatory drugs: mechanism of action, clinical studies and future perspectives