IMAGING AND PHYSICAL-CHEMICAL CHARACTERIZATION OF BIOMATERIALS
This course aims to give students some introductions about the characterization and properties of inorganic and polymeric compounds in the solid state, in particular, as regards the characterization of solid phases through advanced techniques such as microscopy and powder diffraction.
Solid state. Biomaterials and ceramics. Characterization methods: X-ray diffraction, electron microscopy.
Definition of biomaterials and biocompatibility. Review of the chemical bond, definition of solid-state and classification of the main classes of solids and their main defects. Biocompatible materials. Polymeric materials: definition, characteristics, mechanical and chemical-physical properties and uses in medicine. Ceramic materials: definition, synthesis and chemical-physical characteristics, bio-inert, bioactive, bio-absorbable ceramics. Fundamentals of crystallography; general principles of diffractive techniques; illustration of the main electron and X-ray diffraction techniques. Fundamentals of powder diffraction, experimental techniques; polymorphism and phase transitions in solid state. Thermodynamic characterization: thermal analyses. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM): operating principles, electron-matter interaction and signal detection, image generation, interpretations of the images associated with the detected signals, criteria for sample preparation; applications. Energy dispersion microanalysis (EDS).
1 - Lectures' notes
2 - Carlo di Bello, Biomateriali (Introduzione allo studio dei materiali per uso biomedico), Patron Editor
Lectures.
Oral exam. Students have the right to ask to explain, independently and completely, a topic of their choice, among those presented in the lectures, which will not however be exhaustive of the entire interview.