GENERAL PATHOLOGY

General Module

Course Sheet

Course code:

TR12A5B

Academic Year of enrolment:

2018

Year of supply:

2018/2019

Type of Course:

Basic

Degree:

Course of 1st Cycle Degree in IMAGING AND RADIOTHERAPY TECHNIQUES

Disciplinary Sector:

General Pathology

Is part of:

PHYSIOLOGY, GENERAL PATHOLOGY AND MEDICAL STATISTICS

Location:

CHIETI

Credits:

Programme Year:

Professor and Collaborators:

MINCIONE Gabriella

Cycle:

Second semester

Obligatory attendance:

Yes

Hours of classroom activity:

Individual study hours:

Prerequisites:

Requirements
To the whole understanding of the disciplines is required: sufficient knowledge of histology, anatomy, biochemistry and having supported and passed the C.I. of Systematic and Topographic Human Anatomy.

Objectives

LEARNING OBJECTIVES
The teaching of General Pathology contributes to the realization of the educational objective of the Study Programme in Medical Radiology Techniques, for Imaging and Radiotherapy (Article 3 of the REGULATION - Specific training objectives and expected skills. "TRAINING PATTERN 1st year - Finalized in provide a good knowledge of the essential theoretical disciplines that derive from the basic sciences, in the perspective of their subsequent professional application.") providing the student with the scientific basis necessary for the identification not only of pathologies but also of preventive and therapeutic approaches suitable for the protection of individual and community health. In particular, the conceptualization of the disease will be emphasized as a deviation of the general laws aimed at maintaining the state of health.

EXPECTED LEARNING OUTCOMES

• Knowledge and understanding
At the end of the course the student will be able to:
to the different levels of complexity (molecules, cells, tissues, organism), the etiopathogenetic factors underlying the structural and functional alterations found in the pathological processes, as well as the damage response mechanisms and the related disorders.

• Applying knowledge and understanding
The student must also be able to apply the knowledge acquired from the course, integrated with those deriving from previous courses, to the understanding of the pathophysiology of the main human pathologies.
The student will be able to deal with the clinical problem in a rational way both in the diagnostic-therapeutic approach and in the preventive one.

Transversal skills (Soft skills):
¬Making judgments
The student will be able to collect and interpret data useful for defining judgments in an autonomous way.

¬ Communication skills
The student will be able to communicate information to specialist interlocutors and not.
¬ Learning skills
The student, through the methodological criterion that the study of the General Pathology provides, will be able to develop the skills necessary to undertake further studies with a good degree of autonomy.

Contents

Knowledge of physical, chemical, biological and genetic causes responsible for the occurrence of human diseases.
Knowledge of the fundamental cellular and molecular pathogenesis mechanisms of diseases: genetic alterations, mechanisms of inflammation, degeneration processes, changes in cell proliferation.
Knowledge of the pathophysiological and molecular alterations responsible of functional modifications of organs and systems..

Extended Syllabus

Concept of illness and morbid status. Etiologys and pathogenesis. Intrinsic and extrinsic causes of disease. Physical, chemical and viral agents as a cause of illness.
• Inflammation: definition and general characteristics. Acute flogosis: chemical mediators and cells involved; the formation of the exudate; various types of exudate. Phagocytosis. Chronic flogosis.
Thermoregulation. Thermogenesis and heat-dispersion. Non-febrile hyperthermia and hypothermia. Fever: etiopathogenesis of fever; the course of the fever; types of fever; metabolic alterations in fever.
Pathophysiology of the blood. Anaemia: general processes and classification.
Oncology: concepts of hyperplasia, hypertrophy, metaplasia, dysplasia, anaplasia, neoplasia. Benign and malignant tumours. Histogenetic classification of benign and malignant human tumours. Metastasis. The process of carcinogenesis. Concepts of carcinogenicity from chemical, physical and viral agents. Stages of carcinogenesis: initiation, promotion and progression. Oncogenes and oncosuppressors and their role in tumours.

Recommended Bibliography

-J. Anne Marie Maier, Massimo Mariotti “Elementi di Patologia generale e Fisiopatologia”, McGraw Hill, Milano.
-G.M. Pontieri “Patologia e Fisiopatologia Generale” per i corsi di laurea in Professioni Sanitarie Piccin, Padova.
-Teaching material provided by the teacher with express recommendation to the students to use it only as an aid/guide to the preparation of the exam. It is recalled, in fact, that the use of the recommended General Pathology books (exclusive choice of the student) is essential for a correct, useful and easier preparation of the subject. Students are required to perform all the topics indicated in the program even if not included in the teaching material. Finally, students are warned against the use of photocopies of educational material (presumed printouts of the lessons) ABUSIVELY sold at the copy shops.

Teaching Methods

The course will be held through interactive lectures with the aid of iconographic material in Power Point files for a total of 3 CFU corresponding to a total of 30 hours. Individual work on a topic chosen by the student in the context of the contents developed during the lectures and part of the program.

Evaluation methods

Verification of learning:

The assessment method is based on a written and an oral test.
The student must demonstrate have acquired sufficient knowledge:
-the causes and mechanisms underlying inflammation processes;
-the topics of Environmental Pathology, with particular reference to the mechanisms of radiation damage;
-the causes and molecular mechanisms of neoplasia;
-the mechanisms underlying the alterations of thermal homeostasis and anemia.

The examination of the form consists of a written test and an oral test to be held on the same day. The written test is preliminary to the oral examination. If the exam is not completed on the same day due to excessive numbers of students, it is postponed to the following day.
The written test will consist of 10 multiple choice questions (i.e. multiple choice with only one correct answer). The total points of the written test are 30 (3 points for each correct answer, 0 points for each wrong answer). The student must have answered correctly at least 6 out of 10 questions (corresponding to the minimum grade of 18/30). The written test will last 20 minutes.
The oral exam will start with the presentation of an individual work in the form of a thesis or ppt file, the result of research activities on specific topics of the course, as moments of study and application of knowledge, in line with the training objectives previously indicated. This first phase will be followed by an interview on subjects covered during the lectures.

The oral exam will include the evaluation of individual work that will be based on the degree of deepening of the topic under discussion.
For the evaluation of the oral exam, the following assessment schedule will be considered:
DATA-CONTENT: correctness and relevance

DESCRIPTORS:
Complete: 30
Extensive: 29-27
Discrete even with some gaps: 26-24
Fully enough: 23-21
Just enough with obvious shortcomings: 20-18

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DATA-ARGUMENTS: breadth and coherence

DESCRIPTORS:
Rigorous and documented highlighting ability to use the acquired knowledge and to link it in the argumentation:30
Precise and detailed: 29-27

Appropriate: 26-24
Fully enough: 23-21
Just enough: 20-18
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DATA-EXPRESSIVE CORRECTNESS, PROPERTY OF SCIENTIFIC LANGUAGE, COMMUNICATIVE ABILITY

DESCRIPTORS
Refined and original: 30
Clear, flowing and correct: 29-27
Discrete: 26-24
Sufficient: 23-21
Not fully adequate: 20-18
The final mark of the module will derive from the mathematical average of the written test and the oral exam.

To pass the exam you must obtain a grade of not less than 18/30.
To achieve a score of 30/30 cum laude, the student must demonstrate that he/she has acquired excellent knowledge of all the topics covered during the course, being able to link them in a logical and coherent way.
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Contacts/More Information

The publicity of the timetable of the lessons and of the didactic programs is assured by the website of the Study Programme and of the University. The exam session is ensured by the application ESSE3 and by the personal student webpage.
Prof.ssa G. Mincione
Tel. 0871/3554117
E-mail: gabriella.mincione@unich.it
Office hours: take an appointment through e-mail.

Università degli Studi
"G. d'Annunzio"

Chieti - Pescara

Aree