General principles of Toxicology - History and objectives of toxicology - kinetic and dynamic of toxic substances - acute and chronic toxicity, selective toxicity, delayed toxicity, accumulation, factors influencing the toxicological response, allergies, tolerances, mechanisms of toxicity -
Toxicokinetics: Absorption, distribution and excretion of toxic substances - Biotransformation of xenobiotics -
Toxicokinetic Parameters and Clinical Considerations - Cmax, Vd, Clearance, Therapeutic Index and Drug Interactions
Approach to the intoxicated patient - Decontamination - Purification - Antidotism.
Acute drug toxicity - Neurotoxicity, Cardiotoxicity, Hepatotoxicity, Nephrotoxicity
drug addiction - tolerance, dependence and withdrawal syndrome, drug and non-drug dependence,
nicotine, electronic cigarettes, ethanol, GHB, cannabis, cocaine, heroin and morphine alike, drugs derived from OTC, amphetamines and amphetamines alike, natural and synthetic cathinones, old and new spikedelic substances, synthetic cannabinoids, drugs of the poor.
Intoxication from domestic and caustic products
Toxicology of metals and metalloids, organic solvents and vapors, air pollutants, pesticides and other products for agricultural use (insecticides, fungicides, herbicides, rat killers), fungi and animal toxins (vipers, bees, wasps, hornets, spiders and fish), herbs and poisonous plants
Food toxicology - nitrates and nitrites, bisphenol A, parabens, acrylamide, natural and synthetic endocrine disruptors, toxicity from food supplements adverse reactions to foods or their ingredients. Energy drinks and their toxicological aspects. Non-directed toxicity to specific organs: Chemical carcinogenesis - Genetic toxicology - Developmental toxicology.